Please note: The content of this post is my own unless the technical terms are too hard to explain, then the content is copied and pasted. I am not a medical professional and thus the post is my point of view. But the content is science-based and credible. Just because it is a new science, does not necessarily make it quackery.
If renal function is normal, biomarkers based on urine or the urinary excretion rate of a nutrient or its metabolite can be used to assess exposure or status for some trace elements (e.g., chromium, iodine, selenium), the water-soluble B‑complex vitamins, and vitamin C.
Markers that are looked at are Methylmalonic acid (MMA) (Vit B12), Pyridoxic acid (Vit B6), Pantothenic Acid (Vitamin B5), Glutaric Acid, Ascorbic acid (Vitamin C), 3-hydroxy-3-methylglutaric Acid, and Methylcitric Acid.
Results part 9:
Lab Tech comment:
- Low or BDL 4-pyrodoxic acid, ascorbic acid, pantothenic, and N-acetylcysteine may be suggestive of a deficiency/insufficiency in these micronutrients.
- Elevated glutaric acid, methylcitric acid, 3-hydroxy-3-methyl-glutaric acid, 3-hydroxypropionic acid, mevalonic acid, and xanthurenic acid are suggestive of corresponding micronutrient marker deficiency/insufficiency. A low level is insignificant.
Dr Lindenberg’s comment: NAC and B6 are low, but B5 is high.
3-Hydroxy-3methyglutaric acid (Coenzyme Q10) 4.23(result) L / 15 – 49 (range)
3-hydroxy-3-methylglutaric acid is a product of the abnormal breakdown of the amino acid leucine. It is also an intermediate compound in the production of cholesterol.
Coenzyme Q10 is a compound that helps generate energy in your cells. CoQ10 is naturally found in the body, with the highest levels in the heart, liver, kidney, and pancreas. It helps generate energy in cells by making the antioxidant adenosine triphosphate (ATP), which is involved in cell energy transfer, and serves as an antioxidant to protect cells against oxidative stress.
Pantothenic Acid (Vit B5) 4.49 (result) H / <4.4 (range)
High levels of pantothenic acid are common with yeast overgrowth and with supplementation. It is widely found in both plants and animals including meat, vegetables, cereal grains, legumes, eggs, and milk. Pantothenic acid helps the body utilize carbohydrates, proteins, and lipids.
NAC (N-Acetyl-Cysteine / Glutathione Cycle) BDL (result) / <0.13 (range)
N-acetyl cysteine (NAC) comes from the amino acid L-cysteine. Low levels of NAC indicate low glutathione levels. It is important to compare pyroglutamic (7.29 / < 61) with glutathione to determine if the person is not making enough glutathione (low value) or if they are using up too much of their glutathione (high value).
4-Pyridoxic Acid and Xanthurenic acid (Vit B6) BDL (result) / <3 or <4 (range)
Low levels of pyridoxic acid are associated with high oxalates and low neurotransmitter levels.
Ascorbic acid (Vit C) 0.07 / < 81.45
Low ascorbic acid is indicative of low levels of vitamin C. This is because vitamin C has a 6-hour half-life so it is out of the system by first-morning urine.
Vitamin C also plays an important role in immune defence and improves the absorption of nonheme iron, the form of iron present in plant-based foods.
Methylmalonic acid (Vit B12) 0.56 (result) / <3.6 (range)
Methylmalonic and B6 are directly involved with the function of the CBS enzyme and indirectly involved with MTHFR, BHMT and SHMT. When B12 is low, MMA levels in the blood and urine increase.
Blood Vit B12 1164(result) 165 – 698 (range) (2016) / 898 (result) >221 (range) (2018)
PLEASE NOTE: ANY VIEWS REGARDING THE RESULTS ARE MY UNDERSTANDING AND DO NOT SERVE AS PROFESSIONAL ADVICE. THE TREATMENT RECOMMENDATION IS STRICTLY RELATING TO ALEX’S RESULTS AND NOT MEANT FOR SELF-TREATMENT. ALWAYS SPEAK TO YOUR HEALTHCARE PROVIDER BEFORE STARTING ANY TREATMENTS.
