MTHFR part 7: Folate Cycle continues… Citric Acid Cycle

Please note: The content of this post is my own, unless the technical terms is too hard to explain, then the content is copy and pasted. I am not a medical professional and thus the post is my point of view. But the content is science-based and credible. Just because it is a new science, does not necessarily make it quackery. 

The Power House: The Citric Acid or Kreb’s Cycle

The Citric Acid or Kreb’s Cycle happens inside the Mitochondria – inside your cells. Here the conversion of all dietary nutrients are turned into energy. Depending on digestive function, diet, rate of absorption and the presence of any genetic quirks, a problem can occur at any point of the cycle, which may lead to significant metabolic imbalances in the body’s chemistry as well as mitochondrial disorders.

If ACAT is lessen or missing,especailly when overloaded by the NOS, MTHFR,BHMT and CBS, activity in other areas can slow down causing:

  1. More B12 depletion
  2. Cholesterol and fatty acid imbalance
  3. Decreasing Bile salts and taurine production as well as poor cell wall function
  4. Poor breakdown of fats, carbohydrates and proteins to fuel other cells, nerves, tissue and organs.
  5. Rising oxalate levels
  6. Co Q10 reduction
  7. Limited energy for the Urea Cycle and Methionine Cycle

Part of this cycle is the Oxalate Production. Form more on that you can click here. Oxalates are anti-nutrients that interfere with the absorption of minerals, especially calcium and magnesium. Oxalates are found in foods that are normally regarded as healthy. Kale, chard, and other leafy greens are all high in oxalates. So, high oxalate content and the inability to pass the oxalic acid through the urine means that you are not properly absorbing calcium and magnesium, as well as other minerals such as zinc and iron. This can mean not only possible kidney stones, brain fog, and fatigue…but a long list of other potential problems, including fibromyalgia, frequent urinary tract infections, inflammatory bowel disease, hypothyroidism, osteoporosis, asthma and several other symptoms that arise from too many oxalates.

If you are interested in learning more f this cycle, click here for a short video on Khan Academy. Or the notes, click here.

This brings us to the end of the Folic Acid Cycle an very important cycle. This cycle happens at the same time as the Methionine Cycle, which we touched a little bit in the beginning.

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