Please note: The content of this post is my own unless the technical terms are too hard to explain, then the content is copied and pasted. I am not a medical professional and thus the post is my point of view. But the content is science-based and credible. Just because it is a new science, does not necessarily make it quackery.
In 2017/2018 my son’s doctor did a methylation test via a company called DNAlysis.
The Methylation test is only a part of the DNA Health test, so last year I decided to have the complete test done The full test looks at Lipid metabolism, Methylation, Detoxification, Inflammation, Oxidative stress, Bone health, Insulin sensitivity, Vitamin metabolism, and Gluten and Lactose Intolerance.
I will still unpack the results from the test a little later.
In 2017/2018 the methylation test included the MTHFR, MTR, MTRR, CBS and COMT. However, another component was added since – MTHFD1.
MTHFD1
Methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1
MTHFD1 is linked to Choline and Folate Metabolism.
Choline is an essential, water-soluble, vitamin-like substance that is required for maintaining the structure, integrity, and signalling functions of the cell membranes, for neurotransmission and lipid transportation.
Inadequate choline in the body can lead to many problems, including cardiovascular diseases, neuropsychiatric diseases such as Alzheimer’s and schizophrenia, and degenerative diseases like osteoporosis.
The symptoms of choline deficiency include:
- Fatigue
- Muscle aches
- Decreased energy levels
- Mood changes
- Nerve damage
- Fatty liver
The neurotransmitter acetylcholine is synthesized from choline. So, a deficiency of choline leads to a lack of acetylcholine.
The dietary sources of choline include:
- Beef: 68 grams of beef contains 290 mg of choline
- Eggs: A single egg can provide 20-25% of your daily required amount of choline
- Salmon: 110 gms that contains about 62.7 mg of choline
- Chicken liver: 68 gms contains 222mg choline
- Cod: 85 gms contains 248 mg choline
- Cauliflower: A ½ cup of cauliflower contains 24.2 mg choline
- Soyabean oil: 15 ml contains 47.3 mg choline
- Broccoli: 118ml contains 31.3 mg choline
Vegetables that are rich in choline are:
- Broccoli
- Cauliflower
- Brussel sprouts
- Swiss Chard
- Asparagus
- Collard Greens
Some fruits that contain choline are:
- Clementines
- Rhubarb
- Mulberries
- Melon
- Grape Fruit
- Blackberries
- Oranges
- Avocado
- Strawberries
The inadequate consumption of choline can lead to high homocysteine and all the risks associated with hyperhomocysteinemia.
PLEASE NOTE: ANY VIEWS REGARDING THE RESULTS ARE MY UNDERSTANDING AND DO NOT SERVE AS PROFESSIONAL ADVICE. THE TREATMENT RECOMMENDATION IS STRICTLY RELATED TO ALEX’S RESULTS AND NOT MEANT FOR SELF-TREATMENT. ALWAYS SPEAK TO YOUR HEALTHCARE PROVIDER BEFORE STARTING ANY TREATMENTS.