DNAlysis Health/ Mind: Part 4 – Inflammation

Inflammation is the immune system’s response to harmful stimuli


Please note: The content of this post is my own unless the technical terms are too hard to explain, then the content is copied and pasted. I am not a medical professional and thus the post is my point of view. But the content is science-based and credible. Just because it is a new science, does not necessarily make it quackery.

Inflammation is the immune system’s response to harmful stimuli, such as pathogens, damaged cells, toxic compounds, or irradiation, and acts by removing injurious stimuli and initiating the healing process.

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DNA Health

Most of the SNPs tested on this panel had significant impacts with IL-1B-511 A>G being the most impacted. This means that the inflammatory response does not Switch off.

Chronic low-grade inflammation: Your body continues sending inflammatory cells even when there is no outside danger. When the gene does not switch off, the inflammatory response continues.

DNA Mind

Neuroinflammation is recognised as one of the potential mechanisms mediating the onset of a broad range of psychiatric disorders, where studies have shown that abnormal inflammatory responses can result in altered behavioural responses and cognitive deficits. Variations in genes encoding pro-inflammatory cytokines and environmental factors may increase the risk for chronic low-grade inflammation and the development of psychiatric diseases, including neurodegenerative and mood disorders.

The same SNPs were tested for the DNA Mind profile, with the impacts being similar.

The influence of Inflammation on the mind in a way that it decreases the release of dopamine, a neurotransmitter implicated in reward and movement.

CRP G>A GG – The G allele increases the expression of CRP, which is associated with higher levels of CRP in the serum. The G allele has also been associated with AB deposition in the brain.

Individuals carrying variations in IL-1A, IL-1B or IL-1RN have a more active inflammatory response and can be considered to have increased IL-1 activity. This has been linked to an increased risk for chronic, low-grade inflammation and predisposition to a number of mental health disorders.

Doctor’s recommendations:

  • Follow-up HS-CRP-DBS test for current inflammation and/or bloodspot Fatty Acids test
  • Decrease intake of saturated fats and moderate intake of omega 6.
  • Increase intake of omega-3 
  • Other nutrients shown to have beneficial effects on inflammation include ginger and curcumin, anthocyanins and trans-resveratrol from red berries.
  • Diets like the Mediterranean diet

Though there are some who believe that Autism is an inflammatory illness, it is not the cause of Autism. However, studies have shown that Autistic people often have higher levels of inflammation than your non-neurotypical people.

Terms: 

CRP: c-reactive protein test. checks for inflammation in the body. Inflammation can be caused by infection, injury, or chronic disease.

AB Deposition: The deposition of amyloid β protein (Aβ) in the human brain and the generation of neurofibrillary tangles are the histopathological hallmarks of Alzheimer’s disease. Accumulation of Aβ takes place in senile plaques and in cerebrovascular deposits as a result of an imbalance between Aβ production and clearance.

PLEASE NOTE: ANY VIEWS REGARDING THE RESULTS ARE MY UNDERSTANDING AND DO NOT SERVE AS PROFESSIONAL ADVICE. THE TREATMENT RECOMMENDATION IS STRICTLY RELATED TO ALEX’S RESULTS AND NOT MEANT FOR SELF-TREATMENT. ALWAYS SPEAK TO YOUR HEALTHCARE PROVIDER BEFORE STARTING ANY TREATMENTS.


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