Please note: The content of this post is my own unless the technical terms are too hard to explain, then the content is copied and pasted. I am not a medical professional and thus the post is my point of view. But the content is science-based and credible. Just because it is a new science, does not necessarily make it quackery.
The Methylation test that was done previously was actually part of DNA Health, but we were not aware of this, so, if you want to read the full results, you can click here.
But here is a quick summary:
Methylation: A chemical reaction in the body in which a small molecule called a methyl group gets added to DNA, proteins, or other molecules. Adding methyl groups can affect how some molecules act in the body. Methylation of the DNA sequence of a gene may turn the gene “off” or “on” so it does not make a protein.
DNA Health
All around, the results were not very good, most highly impacted.
DNA Mind
The DNA Mnid report also looks at methylation which is part of mood regulation.
Again MTHFR 667 C>T was heavily affected.
Methylation involves the process of creating methyl groups that can be added to a molecule, or substrate, and plays an essential role in the production of neurotransmitters. In order for methylation reactions to be completed, specific amounts of B vitamins are required. B vitamins are nutrients that are derived from the diet. Poor methylation function due to enzymatic deficiencies as well as low levels of B-vitamins have been associated with increased risk of mood disorders.
Essential enzymes for B-vitamin dependant methylation:
- Methylenetetrahydrofolate Reductase (MTHFR) = Riboflavin (Vit B2)
- Methionine Synthase (MTR) = Methyalfolate & cobalamin (Vit B9 and Vit B12)
- Methionine Synthases Reductase (MTRR) = Methylcobalamin (vit B12)
- Cystathionine B-synthase (CBS) = Vit B6
- Methyl transferases (MTs) e.g. Catechol O-methyl transferase (COMT) = Magnesium
Further advice:
- Because of the COMT A allele, ensure adequate magnesium intake
- Because of the MTHFD1 A allele, ensure adequate intake of choline-rich food or supplement
- A follow-up Organic acid test to evaluate methylation and transsulfuration function
PLEASE NOTE: ANY VIEWS REGARDING THE RESULTS ARE MY UNDERSTANDING AND DO NOT SERVE AS PROFESSIONAL ADVICE. THE TREATMENT RECOMMENDATION IS STRICTLY RELATED TO ALEX’S RESULTS AND NOT MEANT FOR SELF-TREATMENT. ALWAYS SPEAK TO YOUR HEALTHCARE PROVIDER BEFORE STARTING ANY TREATMENTS.
